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Buerger disease | Circulatory System and Disease | NCLEX-RN | Khan Academy

Voiceover: What would
happen if you narrow the blood vessels in your
fingers and in your hand? What would you see? What would happen? Well, of course we’d see
decreased blood flow, which means decreased oxygen delivery to the tissues, right. Decreased oxygen delivery to your fingers, which can lead to pain. It’s very similar to what
happens in the heart. If you have decreased
blood flow to the heart, then you can feel anginal pain, right. Angina, chest pain. Here, it’s very similar,
you get a muscular pain, which is known as claudications. Now, what happens if the blockage is so severe that you have complete blockage? It’s no longer narrowed, it’s
just completely blocked off. Well, you’re not going to get any more blood to your fingers, and so it makes sense, they’re going to die. The cells in them are going to die, and your fingers will fall off. This is called autoamputation. These are two of the main symptoms found in the vasculitis called
Buerger’s disease. Recently, there’s been a movement in Medicine in trying to rename diseases that are named after guys like Buerger. And they’re trying to make it easier for people like us to
understand medical terminology, and so they’ve tried to
rename some diseases. In this case, they’ve renamed this thromboangiitis obliterans,
so much for really help us understand what it means, right. Let’s break it down. It may be a mouthful, but when we take a look at it, actually
makes a lot of sense. Thrombo means clotting right. Angitis is inflammation of blood vessels, which is really the root of vasculitis. Remember vasculitis is
vessel inflammation. Angitis is just another name for this. And lastly, obliterans, which is a term for artery occlusion or artery blockage. Obliterans pretty much
just means blockage. So, here we’ve got clot formation, vessel inflammation, and blockage. We can think there is
vessel inflammations, disease causing a clot, which creates a blockage in blood flow. And so you see these symptoms of claudication, autoamputation, death of the cells,
necrotizing vasculitis. Other symptoms that you see
are ischemic ulcers, gangrene. These are all terms for the same thing. Ischemic ulcer: Blood flow, blood decrease causing skin damage. Gangrene: Cell death of fingers and toes, damaged dead cells. This is not just the
hands, actually the feet are involved as well. Most common symptom is
forefoot pain, pain right here. Now, this can be diagnosed
with an ultrasound. Taking a look with a probe and seeing what it displays on the screen. And here, we’ll see
narrowing of blood vessels. Not only that, you can
also use an angiography. Angiography is a way to visualize the inside of blood vessels. What you do is you have
a patient take this fluid called contrast that has a
high radiological isotope. Basically, it can be seen when you use something like an x-ray or
a scan, a radiological scan. And so it gets absorbed into your blood stream and allows
physicians to visualize how the blood vessels look on the inside. So if there is a blockage in the artery, the physician will see this narrowing because there is less
blood flow through an area. Another thing you can see in
angiography is some spiraling. A cork screwing pattern of
arteries around a blockage, so arteries create this
cork screwing because they go through a pattern of
growth, damage, regrowth. They’re trying to create
a new fresh artery. A risk factor of this disease is smoking. The pathophysiology
isn’t quite understood, but it’s believed that
something in the tobacco or something in the cigarette is causing the immune system to respond. And for some reason, vessels in your hands and your feet are affected. The only definitive
treatment is to stop smoking. There is no medication that really can be given to stop the
progress of this disease. So patients are urged to really quit. Otherwise, they may lose
their fingers or toes. If that’s not enough motivation, then I don’t know what else would be.

18 thoughts on “Buerger disease | Circulatory System and Disease | NCLEX-RN | Khan Academy

  1. I've heard this is a disease that only smokers get.  Unlike lung cancer, heart attacks, and strokes, smokers cannot think "Oh, non-smokers get Buerger's too, maybe cigarettes didn't cause it."

  2. its real. it affect my left leg at the age of 18 and im an left above knee amputee "laka" its rare bc very few ppl body rejects nicotine to where it cause amoutation.and also most doctors dont have a clue what it is or why ur in pain with a x-ray. so i suffer until u find a doctor familiar with it or u fought and let it go so long before theres no chance to save it listen to me and trust me its real. quit smoking immedieatly bc theres no cure once u have other than quit smoking and that just puts the diease in intermission only bc the affect body parts are more than likely damaged permaneatly,u continue to smoke after quitting all the past damaged feeds and returns 5x as horrible. a diseases that stales or is put in intermission spreads faster and deadly after it returns like cancer! it affects ur limbs as u can see first and collapses the veins and arteries if not treated after some time the could result in a artery completely decengrating. but really its affecting all artertiers. this diease cause so much pain after amputating i was in so much relief

  3. Just a correction, at 3:10 for angiography studies, the patient is injected with contrast through a catheter, not through ingestion. Ingesting contrast is for GI X-ray series such as a barium swallow. Thanks for the video, it was incredibly helpful

  4. I'm surprised the anti-smoking campaigns haven't grabbed ahold of this. Some people are grossed out by black lungs, but some people are also grossed out by healthy lungs. I'm not sure how effective that is. Showing fingers falling off though…

  5. Thank you for making this video and bringing awareness to this disease. I DO have Buerger's Disease and there is still no cure. This disease usually affects people in their 20's and 30's, and they are not sure exactly why or how, but whoever DOES have this disease, they have either smoked cigarettes or chewed tobacco in their past.The symptoms were slow to develop in me until I was in my late 40's. I await a doctor's appointment next month to determine if I amputate my finger or not; the only treatment is amputations and that is for pain relief only. 🙁 I am currently using Chantix to quit smoking from 1 1/2 packs a day for the last 25 years, down to (Today) 1-2 cigarettes a day. I wish I knew then what I know now. I created a Vlog series called "My Painful Path – Living with Buerger's Disease" where I talk about my life and obstacles I encounter. Please have a peak. Thanks again for bringing awareness to this disease.

  6. Any similar disease for non smokers?
    My 16 year old son doesn’t smoke but
    Has very similar symptoms to this disease .

  7. I've been diagnosed with beuarger disease today and I am desperate condition I don't think I can deal with it
    my fingers are black i am afraid very much !!!!

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